Imaging of Osteoarthritis—Latest Advancements

An updated review of the many recent developments in imaging of osteoarthritis.

Course ID: Q00624 Category:
Modalities: , , , ,


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Targeted CE per ARRT’s Discipline, Category, and Subcategory classification:
[Note: Discipline-specific Targeted CE credits may be less than the total Category A credits approved for this course.]

Computed Tomography: 0.50
Procedures: 0.50
Head, Spine, and Musculoskeletal: 0.50

Magnetic Resonance Imaging: 1.25
Procedures: 1.25
Musculoskeletal: 1.25

Nuclear Medicine Technology: 0.25
Procedures: 0.25
Other Imaging Procedures: 0.25

Radiography: 0.50
Procedures: 0.50
Extremity Procedures: 0.50

Registered Radiologist Assistant: 1.25
Procedures: 1.25
Musculoskeletal and Endocrine Sections: 1.25

Sonography: 0.50
Procedures: 0.50
Superficial Structures and Other Sonographic Procedures: 0.50


  1. Introduction
  2. Radiography
  3. US Imaging
  4. CT Imaging
  5. Nuclear Medicine
  6. Semiquantitative MRI Assessment
  7. Quantitative MRI Analysis of Articular Cartilage
  8. Compositional MRI
  9. Artificial Intelligence in MRI Assessment
  10. Other Joints, Beyond the Knee
  11. Treatments for OA
  12. Outlook for OA


Upon completion of this course, students will:

  1. describe the estimated proportion of the population aged 45 years or older that will have physician-diagnosed knee OA
  2. list the factors that may play an important role in the early stages of osteoarthritis
  3. identify the imaging modality that has traditionally been used to assess osteoarthritis structural changes
  4. identify the most important imaging modality used to evaluate osteoarthritis in a research context
  5. describe the imaging features associated with the different grades of the Kellgren-Lawrence grading scheme
  6. describe the most widely applied radiographic criterion for defining the presence of structural osteoarthritis
  7. identify the Kellgren-Lawrence grade of OA associated with a definite osteophyte on radiographs
  8. describe the use of imaging in phase III clinical trials of OA drugs
  9. identify the radiographic view commonly used to visualize joint space narrowing in the knee
  10. list the strengths of US over other modalities in the assessment of OA
  11. describe the sensitivity of US imaging over radiography in the evaluation of abnormalities in the knee
  12. identify the CT imaging technique that can discriminate meniscal calcium pyrophosphate deposits from calcium hydroxyapatite
  13. describe the temporal resolution of four-dimensional CT used for kinematic CT acquisitions of the knee
  14. identify the CT technique that requires the intra-articular injection of contrast material
  15. list the knee structures which can be assessed accurately with CT arthrography
  16. describe the usefulness of PET imaging in the setting of OA
  17. identify the imaging modality that does not play a role in the diagnosis and decision-making processes of knee OA
  18. describe the first published MRI scoring system that has been used extensively for almost 2 decades in a multitude of OA studies worldwide
  19. list the semiquantitative MRI scoring systems that assess cartilage size and depth on a scale from 0 to 3
  20. list the semiquantitative MRI scoring systems that include assessment of the Hoffa fat pad for synovitis
  21. list the three main structural phenotypes of OA
  22. identify the semiquantitative MRI scoring system that can achieve phenotypic characterization of OA based on a simplified MRI assessment
  23. list the compositional MRI techniques that assess glycosaminoglycans in cartilage
  24. list the compositional MRI techniques that can be limited by magic angle effects
  25. describe the location of regional cartilage thickening that may be an early event in OA pathophysiology
  26. list the OA treatments that are evaluated using quantitative MRI measurements of cartilage volume and thickness change
  27. identify the compositional MRI techniques that have been used to evaluate OA in most research studies
  28. describe the use of compositional MRI using T2 quantification in the assessment of OA
  29. identify the body joints where T1ρ mapping has been shown to be a predictor of OA progression.
  30. list the tissues that have been successfully segmented using deep learning approaches in fully automated MRI segmentation
  31. describe the use of deep learning methods to assign grades to assess OA severity on knee radiographs
  32. list the OA-associated structural joint pathologies that can be identified by MRI deep learning approaches
  33. describe subtle but clinically relevant changes at MRI that may be missed by deep learning neural networks
  34. list the reasons why less attention has been paid to imaging OA in the hip
  35. describe the evaluation focus of the Hip Inflammation MRI Scoring System
  36. identify the imaging techniques that can assess the biochemical composition of cartilage
  37. identify the imaging techniques associated with a long imaging time
  38. describe the compositional MRI technique used to evaluate the hip prior to acetabular osteotomy in patients with developmental hip dysplasia
  39. describe treatments for OA based on the recommended hierarchy of management
  40. identify the class of drugs associated with safety concerns during clinical trials