Lymphoscintigraphy and Sentinel Nodes

A discussion of sentinel lymph node procedures that include lymphoscintigraphy in the setting of malignancies to the skin, breast, head, and neck.

Course ID: Q00458 Category:
Modalities: , , ,


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Targeted CE per ARRT’s Discipline, Category, and Subcategory classification:
[Note: Discipline-specific Targeted CE credits may be less than the total Category A credits approved for this course.]

Mammography: 1.00
Procedures: 1.00
Mammographic Positioning, Special Needs, and Imaging Procedures: 1.00

Nuclear Medicine Technology: 1.50
Procedures: 1.50
Endocrine and Oncology Procedures: 1.50

Registered Radiologist Assistant: 1.00
Procedures: 1.00
Thoracic Section: 1.00


  1. Introduction
  2. Lymphoscintigraphy in SLN Procedures
    1. Procedure for SLN Lymphoscintigraphy
    2. Radiopharmaceuticals and Injection Parameters
    3. Imaging
  3. Cancer Indications
    1. Breast Cancer
    2. Melanoma
    3. Head and Neck Malignancies
  4. Radiation Risks
  5. Summary


Upon completion of this course, students will:

  1. be familiar with the validation of SLNB for breast cancer
  2. be familiar with the growth and development of lymphoscintigraphy
  3. be able to identify who is credited with the introduction of SLNB based on radiotracer techniques
  4. be familiar with techniques used to minimize pain during lymphoscintigraphy
  5. be able to identify the radiopharmaceuticals used to perform lymphoscintigraphy
  6. be familiar with the injection technique for performing lymphoscintigraphy in patients with melanoma
  7. be familiar with the injection techniques for performing lymphoscintigraphy in patients with breast cancer
  8. be familiar with the different imaging techniques employed in lymphoscintigraphy
  9. be familiar with the imaging procedure used to perform lymphoscintigraphy on patients with melanoma
  10. be familiar with the planar projections acquired when performing lymphoscintigraphy on patients with breast cancer
  11. be familiar with the technique for skin markings once SLNs are visualized on lymphoscintigraphy
  12. compare the patient outcomes between SLNB and ALND
  13. be familiar with the aims of SLNB in regards to false-negative rates
  14. identify the clinical circumstances in which SLNB is utilized
  15. be familiar with the criteria for performing SLN procedures for multicentric breast cancer
  16. be familiar with the use of neoadjuvant chemotherapy
  17. be familiar with the benefits of SLNB as compared to ALND
  18. identify the clinical trial with the lowest false-negative rate in Table 1
  19. identify the false-negative rates of the various clinical trials
  20. be familiar with the lesion characteristics used to stage the invasiveness of melanoma
  21. be familiar with the criteria for performing SLNB in patients with melanoma
  22. identify the ability of elective complete lymph node dissection to reveal metastases in melanoma patients
  23. identify the percent of risk associated with melanoma thickness of greater than 4mm
  24. be familiar with the primary goal of the Multicenter Selective Lymphadenectomy Trial 1
  25. be familiar with the design question of the Multicenter Selective Lymphadenectomy Trial 2
  26. be familiar with criteria for using SLNB in patients with oral squamous cell cancer
  27. be familiar with the advantages of using SPECT/CT when performing head and neck lymphoscintigraphy
  28. be familiar with a method to reduce potential contamination when performing head and neck lymphoscintigraphy
  29. identify the radiopharmaceutical that has been FDA-approved for use in the management of oral squamous cell carcinoma
  30. be familiar with the use of SLNB for lymph node staging in breast cancer and melanoma