CT Perfusion of the Liver

Various oncologic applications of CT perfusion are discussed and current challenges, as well as possible solutions, for CT perfusion are presented.

Course ID: Q00429 Category:
Modalities: ,

3.0

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$34.00

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This course has been approved for 3.0 Category A credits.
No discipline-specific Targeted CE credit is currently offered by this course.

Outline

  1. Introduction
  2. Basic Principles of CT Perfusion Imaging
  3. CT Acquisition Protocol
  4. Calculation of CT Perfusion Parameters
    1. Single-Input versus Dual-Input Model
    2. Single-Compartment versus Dual-Compartment Model
    3. Dual-Compartment Model versus Distributed Parameter Model
  5. CT Perfusion Parameters
  6. Applications in Clinical Oncologic Imaging of the Liver
    1. General Introduction: Alteration of CT Perfusion Parameters in Liver tumors
    2. Early Detection of Liver Tumors
    3. Assessment of Prognosis Based on Tumor Perfusion
    4. Monitoring Therapeutic Effects
    5. Diagnosing Tumor Recurrence
  7. Current Challenges and Future Directions
    1. Radiation Dose
    2. Protocol Standardization
    3. Reproducibility
    4. Motion Correction
    5. Other Issues
  8. Conclusion

Objectives

Upon completion of this course, students will:

  1. be familiar with morphological imaging techniques used to diagnose liver disease
  2. identify challenges when performing CT perfusion imaging of the liver
  3. identify the disadvantages of assessing tumor specimen with needle biopsy
  4. be familiar with the first phase of tissue enhancement during CT perfusion imaging of the liver
  5. be familiar with the second phase of tissue enhancement during CT perfusion imaging of the liver
  6. understand the unique blood supply to the liver
  7. be familiar with the timing of the first phase of CT perfusion imaging of the liver
  8. be knowledgeable about the minimum concentration of iodine used in CT perfusion imaging of the liver
  9. identify the recommended rate of contrast media injection for CT perfusion imaging of the liver
  10. recognize the percentage of blood flow to the portal vein in the liver
  11. identify how the HAP is separated from the PVP
  12. be able to define HPI
  13. be familiar with the evolution of hepatocellular dysplastic nodules to HCC
  14. be able to define MTT
  15. be able to define extraction fraction
  16. understand the effects of arteriovenous shunts on the MTT
  17. identify the clinical application of CT perfusion imaging of the liver
  18. be familiar with the advantages of early detection rates in HCC
  19. be able to identify the process of confirmation of earlier detection of liver metastases with CT perfusion imaging of the liver
  20. be able to define tumor angiogenesis
  21. be familiar with the use of antiangiogenic drugs for therapeutic treatment
  22. be familiar with the techniques used to reduce radiation exposure during CT perfusion imaging of the liver
  23. identify the current challenges for performing CT perfusion imaging of the liver
  24. understand the reason to use motion correction when performing CT perfusion imaging of the liver