

Radionuclide Imaging in Ischemic Stroke
Radioactive tracers and applications of radioisotope studies in stroke evaluation are presented. Future perspectives using hybrid imaging are discussed.
Course ID: Q00423 Category: Radiology Trends for Technologists Modalities: Nuclear Medicine, PET2.5 |
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$29.00
- Targeted CE
- Outline
- Objectives
Targeted CE per ARRT’s Discipline, Category, and Subcategory classification:
[Note: Discipline-specific Targeted CE credits may be less than the total Category A credits approved for this course.]
Nuclear Medicine Technology: 1.50
Procedures: 1.50
Other Imaging Procedures: 1.50
Outline
- Introduction
- Physiologic Variables Affected in Ischemic Stroke
- Radioactive Tracers Used in Stroke
- Applications of Radioisotope Studies in Stroke
- Detection of Ischemic Lesion
- Identification of the Ischemic Penumbra
- Noninvasive Imaging of the Penumbra
- Radioisotope Imaging as a Surrogate Marker for Treatment Efficiency and for Selection of Patients for Special Therapeutic Strategies
- Microglial Activation as an Indicator of Inflammation
- Hemodynamic and Metabolic Reserve in Arterial Occlusive Disease
- Deactivation of Remote Tissue (Diaschisis
- Activation Studies in Stroke Patients
- Conclusion and Future Perspectives
Objectives
Upon completion of this course, students will:
- define the term malignant as it applies to brain infarction
- identify the gas used in the first quantitative method of measuring CBF
- list the radioactive gases used for imaging studies of rCBF
- list the vascular components of the CBV
- describe the percentage of total-body glucose consumption used by the brain at rest
- describe the time it takes for loss of consciousness to occur following stoppage of CBF
- list the characteristics of SPECT radiopharmaceuticals used for stroke evaluation
- list the isotopes used in PET radiopharmaceuticals for stroke evaluation
- describe the final structure of the PET radiopharmaceutical used for evaluation of glucose metabolism
- compare the sensitivities of SPECT, PET and CT for detection of the presence and extent of stroke
- describe the effect of SPECT imaging on neurologic deficit scores
- identify the region of the brain with the potential for functional recovery without morphologic damage following acute ischemic stroke
- describe the difficulties with using SPECT perfusion studies in identifying hypoperfused tissue that is amenable to reperfusion therapy
- compare the accuracies of MR DWI and PWI in identifying the ischemic penumbra and predicting infarcted tissue
- describe the use of the PET radiopharmaceutical 18F-fluoromisonidazole
- identify the vessel territory associated with malignant brain infarcts in 10% of patients
- list the imaging techniques that can identify selective neuronal loss in the cortex resulting from exhausted metabolic reserve
- indicate the brain region most frequently affected by post-stroke aphasia in right-handed individuals with left hemispheric language dominance
- identify the best method for imaging the morphology of the brain in health and disease
- identify the PET radiopharmaceutical that is part of an innovative strategy for imaging evaluation of angiogenesis