Molecular Body Imaging with MRI, CT and US, Part I

Principles of molecular imaging are presented using emerging technologies in MRI, CT, and US.

Course ID: Q00340 Category:
Modalities: , , ,

2.5

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Targeted CE per ARRT’s Discipline, Category, and Subcategory classification:
[Note: Discipline-specific Targeted CE credits may be less than the total Category A credits approved for this course.]

Magnetic Resonance Imaging: 0.50
Patient Care: 0.50
Patient Interactions and Management: 0.50

Nuclear Medicine Technology: 0.25
Patient Care: 0.25
Patient Interactions and Management: 0.25

Registered Radiologist Assistant: 0.25
Patient Care: 0.25
Pharmacology: 0.25

Sonography: 0.25
Patient Care: 0.25
Patient Interactions and Management: 0.25

Outline

  1. Introduction
  2. Molecular MR Imaging
  3. Principles of MR Contrast Agents
    1. T2 and T1 Contrast Agents
    2. Contrast Agents Based on Fluorine 19
    3. Chemical Exchange Saturation Transfer Agents
    4. Activatable MR Contrast Agents
    5. Multimodality Probes
    6. Hyperpolarization
  4. Molecular CT Imaging
  5. Principles of Molecular CT Contrast Agents
  6. Molecular US Imaging
  7. Principles of Molecular US Contrast Agents
  8. Quantification of Molecular US Imaging Signal By Using US Contrast Microbubbles

Objectives

Upon completion of this course, students will:

  1. understand the drawbacks of PET imaging
  2. recognize the imaging modalities that currently provide anatomic information
  3. recognize the imaging modalities that provide the highest contrast sensitivity
  4. understand the effects of a T1 MRI contrast agent
  5. recognize examples of superparamagnetic iron oxide nanoparticles
  6. understand the process of iron oxide nanoparticle filtration and excretion
  7. be familiar with the characteristics of ultrasmall superparamagnetic iron oxide particles
  8. be familiar with the characteristics of gadolinium
  9. recognize the characteristics of new gadolinium-containing molecular MR agents
  10. be familiar with the elemental targets of MR imaging
  11. understand the benefits and drawbacks of MR imaging with fluorine-19
  12. be familiar with intrinsic tissue properties highlighted by contrast-enhanced MR imaging
  13. know the components of targeted PARACEST MR agents
  14. define the concept of multiplexing
  15. understand the fundamentals of activatable MR contrast agents
  16. know the terminology of activatable MR contrast agents
  17. understand the effects of magnetic relaxation switching
  18. recognize the benefits of MRI as a basis for multimodality probes
  19. differentiate the use of radioactive and non-radioactive gases
  20. recognize the benefits of hyperpolarization
  21. understand the basics of nuclear magnetic alignment
  22. recognize the benefits of CT imaging
  23. understand the requirements of CT contrast agents
  24. recognize the drawbacks of current non-targeted CT contrast agents
  25. distinguish the components of molecular CT agents from other modalities
  26. identify the characteristics of a bismuth sulfide molecular CT agent
  27. recognize the benefits of US imaging
  28. compare the benefit of a targeted US agent over a non-targeted agent
  29. understand the physical principles of imaging US microbubbles
  30. be familiar with the characteristics of non-microbubble ultrasound contrast agents
  31. understand the metabolic and excretory pathway of an ultrasound microbubble
  32. understand the concentrations of current non-targeted ultrasound microbubbles
  33. identify current uses of non-targeted ultrasound microbubbles
  34. recognize the features of absolute quantitative ultrasound analysis
  35. identify the modalities that employ semiquantitative analysis techniques