CT of Pulmonary Sarcoidosis

The role of high-resolution CT in the diagnosis and management of pulmonary sarcoidosis.

Course ID: Q00329 Category:
Modalities: ,


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Targeted CE per ARRT’s Discipline, Category, and Subcategory classification:
[Note: Discipline-specific Targeted CE credits may be less than the total Category A credits approved for this course.]

Computed Tomography: 2.00
Procedures: 2.00
Neck and Chest: 2.00

Radiography: 1.00
Procedures: 1.00
Thorax and Abdomen Procedures: 1.00

Registered Radiologist Assistant: 2.50
Procedures: 2.50
Thoracic Section: 2.50


  1. Introduction
  2. Epidemiology
  3. Clinical Features
  4. Pathogenesis
  5. Histologic Findings
  6. Staging and Prognosis
  7. Diagnosis
  8. Use of High-Resolution CT
  9. Radiologic-Pathologic Correlation
  10. Typical Patterns of Lymphadenopathy
  11. Atypical Patterns of Lymphadenopathy
  12. Typical Parenchymal Manifestations
    1. Micronodules with a Perilymphatic Distribution
    2. Fibrotic Changes
    3. Bilateral Perihilar Opacities
  13. Atypical Parenchymal Manifestations
    1. Pulmonary Nodules and Masses
    2. Patchy Airspace Consolidation
    3. Patchy Ground-Glass Opacities
    4. Linear Reticular Opacities
    5. Fibrocystic Changes
      1. Honeycomb-like Cysts
      2. Cavitation of Parenchymal Lesions
      3. Mycetoma Formation
    6. Miliary Opacities
    7. Airway Involvement
      1. Mosaic Attenuation Pattern
      2. Air Trapping
      3. Tracheobronchial Abnormalities
      4. Atelectasis
    8. Pleural Disease
    9. Pleural Plaquelike Opacities
  14. Conclusions


Upon completion of this course, students will:

  1. identify what percentage of sarcoidosis patients develop pulmonary fibrosis
  2. be familiar with the initial radiologic test performed when diagnosing sarcoidosis
  3. identify how pulmonary sarcoidosis may initially manifest in patients
  4. identify the most typical finding of pulmonary involvement in sarcoidosis patients
  5. be familiar with organs initially affected by sarcoidosis
  6. be familiar with signs and symptoms of sarcoidosis patients
  7. identify the skin symptoms exhibited by sarcoidosis patients
  8. be familiar with the most common areas of the lungs affected by sarcoidosis
  9. identify which patient populations are most affected by sarcoidosis
  10. understand the prognosis criteria for patients suffering from sarcoidosis
  11. understand what causes epitheliod cell granulomas associated with sarcoidosis
  12. be familiar with the proteins created by lymphocytes on the granulomas
  13. identify which lobes of the lungs are affected by sarcoidosis
  14. be familiar with the diagnostic findings used for sarcoidosis
  15. be familiar with the scientist credited for developing the sarcoidosis staging system
  16. identify what diagnostic radiological test is used in staging sarcoidosis patients
  17. identify the stages of sarcoidosis that are defined under the current system
  18. understand the criteria used to stage sarcoidosis
  19. be familiar with the remission probability for sarcoidosis
  20. identify advances in bronchial imaging
  21. describe the technical advantages of high-resolution CT in detecting sarcoidosis
  22. understand the ability of high-resolution CT to differentiate forms of sarcoidosis
  23. identify the typical pattern of disease on a high-resolution CT when lymphadenopathy is present
  24. be familiar with the common cause of bilateral lymph node enlargement in patients
  25. identify the prevalent age group for lymphadenopathy
  26. be familiar with the perilymphatic distribution of micronodular lesions
  27. identify the frequent causes of nodular or irregular thickening of the peribronchovascular interstitium
  28. be familiar with the effects of extensive interstitial fibrosis
  29. identify the typical parenchymal manifestation of sarcoidosis in patients
  30. be familiar with the “galaxy sign” as seen in sarcoidosis patients
  31. be familiar with the high-resolution CT sign created by multiple micronodules along lymph vessels
  32. identify the patterns associated with atypical patchy airspace consolidations
  33. be familiar with the diseases that create patchy airspace consolidations
  34. identify the fibrocystic high-resolution CT patterns for sarcoidosis
  35. identify the fibrocystic patterns of sarcoidosis that simulate idiopathic pulmonary fibrosis
  36. be familiar with the cause of aspergillus that affects some sarcoidosis patients
  37. identify the second most common cause of death among patients with sarcoidosis
  38. be familiar with the mosaic attenuation pattern seen with high-resolution CT
  39. be familiar with the prevalence of pleural effusions and the time to recovery in sarcoidosis patients
  40. understand the need for differential diagnosis when patients are suspected of having sarcoidosis