Diffusion-Weighted MRI of the Liver

A look at how advances in MRI system hardware and coil technology allow diffusion-weighted sequences to aid in liver lesion detection and characterization as well as act as a therapeutic indicator.

Course ID: Q00292 Category:
Modalities: ,


Satisfaction Guarantee


Targeted CE per ARRT’s Discipline, Category, and Subcategory classification for enrollments starting after February 8, 2023:
[Note: Discipline-specific Targeted CE credits may be less than the total Category A credits approved for this course.]

Magnetic Resonance Imaging: 3.25
Image Production: 2.25
Sequence Parameters and Options: 0.50
Data Acquisition, Processing, and Storage: 1.75
Procedures: 1.00
Body: 1.00

Registered Radiologist Assistant: 1.00
Procedures: 1.00
Abdominal Section: 1.00


  1. Introduction
  2. Principles of Diffusion-weighted Imaging of the Liver
  3. Liver Diffusion Imaging Acquisition, Optimization, and Display
    1. DW MR Imaging Acquisition Techniques
    2. Choice of b Values and Sequence Optimization
    3. Image Display and Processing
    4. ADC Reproducibility
    5. Current Applications of Liver DW MR Imaging: Liver Lesion Detection
    6. Current Applications of Liver DW MR Imaging: Liver Lesion Characterization
    7. DW MR Imaging in Assessment of Tumor Response to Treatment
    8. Diagnosis of Liver Fibrosis and Cirrhosis with DW MR Imaging
    9. Estimation of Tumor Perfusion with IVIM DW MR Imaging
  4. Limitations of DW MR Imaging Technique in the Liver
  5. Future Directions
  6. Conclusions


Upon completion of this course, students will:

  1. understand how to incorporate DW MR imaging into existing protocols
  2. identify why MR is useful in evaluating patients with liver disease
  3. understand the foundations of the principles of DW MR imaging
  4. understand the process of diffusion
  5. understand how DW MR image contrast is calculated
  6. identify the difference between restricted and relatively free apparent diffusion
  7. understand how diffusion is observed and measured
  8. understand the different diffusion directions measured
  9. understand the role of the b value in DW MR imaging of the liver
  10. identify the number of b values needed to quantify ADC values
  11. understand the information obtained from ROI quantification
  12. be familiar with the IVIM phenomenon
  13. understand advantages of specific DW MR imaging techniques
  14. understand the challenges of specific DW MR imaging techniques
  15. understand trade-offs of sequence optimization
  16. be familiar with the useful range of b values used in DW MR liver imaging
  17. understand the importance of utilizing low b values
  18. understand the importance of utilizing high b values
  19. identify trace images
  20. understand the importance of qualitative visual assessment in detecting liver lesions
  21. understand T2 shine-through
  22. identify lesions based on visual assessment of b value images and ADC maps
  23. understand quantitative assessment of ADC maps
  24. be familiar with the unit of measurement expressing the ADC of tissue
  25. understand reasons for variation in the ADC measurements
  26. understand why lesion detection is improved with DW MR imaging vs T2W imaging
  27. understand the benefit of DW MR imaging in patients with impaired renal function
  28. understand visual comparisons in liver lesion characterization
  29. be familiar with the accuracy of visual assessment in liver lesion characterization
  30. understand the role of published ADC values in identifying liver lesions
  31. be familiar with the therapies that DW MR imaging can measure tumor response to treament
  32. identify an effective treatment response
  33. identify the potential predictive value of the DW MR imaging technique
  34. understand how cirrhosis is diagnosed with DW MR imaing
  35. understand the changes in diffusion in patients with liver fibrosis
  36. understand which b value contributes perfusion information
  37. understand limitations of DW MR imaging techniques in the liver
  38. understand the key solution to improve image quality
  39. be familiar with the potential benefits of DW MR imaging at high field
  40. understand how to avoid limitations of the DW MR technique