PET-CT Imaging and FDG Uptake

The use of fused PET and CT images in differentiating physiological from pathological FDG uptake is presented.

Course ID: Q00183 Category:
Modalities: ,


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Targeted CE per ARRT’s Discipline, Category, and Subcategory classification:
[Note: Discipline-specific Targeted CE credits may be less than the total Category A credits approved for this course.]

Nuclear Medicine Technology: 2.50
Procedures: 2.50
Endocrine and Oncology Procedures: 2.50

Registered Radiologist Assistant: 2.50
Procedures: 2.50
Abdominal Section: 0.75
Thoracic Section: 0.75
Musculoskeletal and Endocrine Sections: 0.25
Neurological, Vascular, and Lymphatic Sections: 0.75

Radiation Therapy: 1.75
Patient Care: 1.75
Patient and Medical Record Management: 1.75


  1. Introduction
  2. Sites of Physiologic FDG Uptake
  3. Physiologic versus Pathologic FDG Uptake in the Head and Neck
  4. Physiologic versus Pathologic FDG Uptake in the Chest
  5. Physiologic versus Pathologic FDG Uptake in the Abdomen and Pelvis
  6. Conclusion


Upon completion of this course, students will:

  1. understand the purpose of the article
  2. know what types of information CT provides
  3. know what types of information PET provides
  4. knowwhat types of information FDG provides
  5. know why CT and PET are combined
  6. be familair with how FDG is taken up
  7. identify normal FDG accumulation
  8. identify abnormal FDG accumulation
  9. be able to describe why specificity is increased when using PET/CT
  10. be able to describe why sensitivity is increased when using PET/CT
  11. be familiar with the pitfalls of PET imaging
  12. know what organ demonstrates the most normal uptake
  13. know why the brain demonstrates intense FDG uptake
  14. be able to identify what the primary substrate for the myocardium is
  15. understand why FDG accumulates in the myocardium
  16. know what factors will reduce myocardial FDG uptake
  17. understand why FDG is seen in the urinary tract
  18. understand what environmental factors can change the outcome of the PET scan
  19. understand what patient’s physical factors can change the outcome of the PET scan
  20. know what muscles can show uptake due to breathing
  21. know the parts of Waldeyer’s ring
  22. be familair with what affects FDG concentrations in the saliva
  23. be familiar with the origin of muscle uptake in the neck
  24. understand how muscle uptake can inhibit scan interpratation
  25. know what causes thymic regression
  26. understand why brown adipose tissue takes up FDG
  27. understand what can reduce the appearance of brown adipose tissue
  28. understand why PET/CT imaging is not always useful
  29. be familair with reasons for FDG uptake in the gallbladder
  30. know what misdiagnoses ureter uptake of FDG can lead to
  31. be familiar with what diseases can affect normal uptake in other organs
  32. understand why CT is an important correlative tool
  33. understand the importance of proper patient preparation
  34. know why fusion software using two different scanners is not as good as PET/CT
  35. be familiar with how patient motion can affect the scan